Home > Working Groups > Pharmacokinetics > Samantha Gouw

Pharmacokinetics

Dr. Samantha Gouw
MD, PhD

Samantha C. Gouw, MD, PhD is trained as a pediatric hematologist and clinical epidemiologist. She received her PhD doctorate on the etiology of inhibitor development in children with severe hemophilia A at Utrecht University in 2011. In collaboration with a team of international colleagues, she published several papers in Blood and New England Journal of Medicine on genetic and non-genetic risk factors of inhibitor development. She currently works as a clinician-researcher at the Department of Pediatric Hematology at the Amsterdam University Medical Center. She is the coordinating researcher of a nationwide study and biobank in hemophilia patients at the Department of Clinical Epidemiology at Leiden University Medical center, The Netherlands and is a work package leader in the National Symphony Consortium. Her current research focuses on inhibitor development and immune tolerance induction and the quality of hemophilia care, especially e-health and value based health care.

Key Publications

Current Positions/Chairs:

  • Clinician - Researcher

Key Institutions

  • Amsterdam University Medical Center
    Pediatric Hematology
    Amsterdam, Netherlands

Research Activities

  • FREE study, effects of emicizumab prophylaxis in severe hemophilia A. Initiator and coordinating researcher, supervision of L. van Stam, PhD student
  • GRIP study, role of Fc gamma receptors in immune tolerance to FVIII. Initiator and supervision of I. Oomen, PhD student
  • Symphony E-Health & Value-based health care coagulation disorders. Workpackage leader E-Health, supervision M.R. Brands, E.S. van Hoorn, PhD students.
  • DYNAMO, The Dynamic interplay between bleeding phenotype and baseline factor level in moderate and mild hemophilia A and B’. Supervision of A.F. Zwagemaker, F. Kloosterman, PhD students.